Anemia Research Today is a free monthly online journal that collates and summarizes the latest research about Anemia, including details on symptoms, diagnosis, diet, treatment, causes.

Microcytosis in agnogenic myeloid metaplasia: prevalence and clinical correlates.

Tefferi A, Dingli D, Li CY, Mesa RA

Division of Hematology, 200 First Street SW, Mayo Clinic, Rochester, MN 55905, USA. tefferi.ayalew@mayo.edu

Microcytosis is a characteristic laboratory feature for both iron deficiency anemia and thalassemia. It is also infrequently seen in "anemia of chronic disease" that accompanies a spectrum of chronic conditions including rheumatoid arthritis, polymyalgia rheumatica, diabetes mellitus, connective tissue disease, and protracted infection. In addition, there is a well established but pathogenetically obscure association of microcytosis with Hodgkin's lymphoma, Castleman's disease, and renal cell carcinoma. In the current study, we show that microcytosis is a frequent laboratory feature in agnogenic myeloid metaplasia and investigate its clinical relevance in the particular setting.

Published 28 March 2006 in Leuk Res, 30(6): 677-80.
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